Biochemistry & Biomedical Sciences
Assistant Professor, Department of Biochemistry and Biomedical Sciences McMaster University
The Miller Laboratory is focused on understanding the intimate relationship between viral pathogens and their hosts. Upon infection, both the innate and the adaptive branches of the immune system are mobilized with the aim of protecting the host from virus-mediated pathologies. However, improper regulation of anti-viral immune responses can themselves lead to disease. In addition, viruses have - and continue to - evolve elegant strategies through which to avoid host-mediated immune recognition. Thus, understanding the qualities of immune responses which are effective in protecting the host, as well as those qualities that may cause harm, is essential to informing the development of novel vaccines and therapeutics.