Sean Egan

Biography

The Egan lab uses animal models to study development of the mammary gland and lung as well as cancer in both tissues.  For example, we use gene targeting to design models for breast cancer which can be probed to define cooperative signaling networks involved in transformation and metastasis, and that can be targeted in the clinic. 

Research Interest

Analysis of the Fringe/Notch signaling system in mammary development/breast cancer