Clayton Dickson
physiology
University of Alberta
Canada
Biography
P439 Biological Sciences Building University of Alberta Edmonton, Alberta Canada T6G 2E9 Tel: 780 492-7860.
Research Interest
Research Description A fundamental question in neurophysiology is how the activity of the nervous system translates, represents, stores, and then uses information in order to guide adaptive behaviour. Our laboratory is interested in how collective activity in large sets of neurons (ensembles) is coordinated within and across areas of the medial temporal lobe of the brain that are known to be important for declarative memory processes. This ensemble coordination is expressed as different patterns of oscillatory synchronization that are dependent upon behavioural state and thus reflect differential processing dynamics of the underlying neural circuitry. We use a wide variety of multichannel recording techniques (from intracellular to multiple single unit and EEG) in a variety of preparations (from brain slices right on up to behaving animals) in order to characterize the mechanisms and functional relevance of oscillatory dynamics in medial temporal lobe structures like the hippocampus and entorhinal cortex.
Publications
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Slow periodic events and their transition to gamma oscillations in the entorhinal cortex of the isolated Guinea pig brain.
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Hippocampal slow oscillation: a novel EEG state and its coordination with ongoing neocortical activity.
