David Stuart
Associate Professor
Biochemistry
University of Alberta
Canada
Biography
Cell division and proliferation are driven by the action of Cyclin Dependent protein Kinases (CDKs) in conjunction with their regulatory subunits, cyclins. Inappropriate activation of cyclin/CDK complexes can drive unregulated cell division resulting in cell death or tumor formation. Cyclin/Cdk complexes also play essential roles in cellular development and differentiation processes. For example meiosis and the formation of gametes in all eukaryotic cells is strictly dependent upon Cyclin/CDK activity. Because of their crucial roles in cell proliferation and development cyclin/CDK expression and activity have multiple forms of regulation imposed upon them. Work in my laboratory is focused on understanding the mechanisms that regulate cell division and differentiation
Research Interest
Biochemistry
