John Seubert
Professor
pharmacology
University of Alberta
Canada
Biography
BSc Biology (Emphasis Toxicology) and Minor in Psychology, 1992, Simon Fraser University, Burnaby, BC, Canada MSc Biology - Aquatic Toxicology (Modulators of Toxicokinetics), 1997, Simon Fraser University, Burnaby, BC, Canada. Advisor: Dr. CJ Kennedy PhD Pharmacology and Toxicology (Molecular Toxicology), 2002, University of Western Ontario, London, Ontario, Canada. Advisor: Dr. JR Bend PDF Cardiovascular Pharmacology, 2002-2005, National Institute of Environmental Health Sciences, RTP, NC. Advisor: Dr. DC Zeldin BSc Biology (Emphasis Toxicology) and Minor in Psychology, 1992, Simon Fraser University, Burnaby, BC, Canada MSc Biology - Aquatic Toxicology (Modulators of Toxicokinetics), 1997, Simon Fraser University, Burnaby, BC, Canada. Advisor: Dr. CJ Kennedy PhD Pharmacology and Toxicology (Molecular Toxicology), 2002, University of Western Ontario, London, Ontario, Canada. Advisor: Dr. JR Bend PDF Cardiovascular Pharmacology, 2002-2005, National Institute of Environmental Health Sciences, RTP, NC. Advisor: Dr. DC Zeldin
Research Interest
Research in our lab is focused on investigating novel epoxy metabolites generated from the metabolism of polyunsaturated fatty acids. We primarily investigate the role of CYP epoxygenase metabolites of arachidonic acid (omega-6), called epoxyeicosatrieanoic acids (EETs), in maintaining tissue homeostasis and reducing injury. However, we have recently begun exploring the CYP-derived metabolites of docosahexaenoic acid (omega-3), called epoxydocosapentaenoic acids (EDPs). The main areas of specialization include cardioprotection, ischemia-reperfusion, PUFA, mitochondria, toxicology, cytochrome P450 system and mechanisms of cellular death.
