Liang Li

Biography

prof. Li’s group is based in the Chemistry Department of the University of Alberta. U of A is located in beautiful Edmonton, Alberta, Canada. button3We work on developing analytical mass spectrometr.

Research Interest

Our group’s research is in the area of analytical mass spectrometry (MS). The major objectives of the research are to develop advanced methods and strategies, primarily based on MS, for the detection and characterization of biological molecules, including peptides, proteins, and metabolites, and to apply these methods to study real-world biological systems. The latter is being accomplished through active collaboration with researchers at the forefront of their disciplines.Our group is particularly interested in the analysis of biosystems, such as organelles, cells, tissues, and body fluids, by an interdisciplinary research approach that uses advanced analytical technologies and sophisticated bioinformatics tools to produce, interrelate, and integrate a large body of chemical and biological information on a biological system. Unlike medicine and systems biology, where more emphasis is on an overall understanding of the functions in a biological system, biosystems analysis focuses on the process of data generation and integration. Thus it can be considered as an important and fundamental part of systems biology and medicine. Biosystems analysis requires analytical technologies having high sensitivity, specificity, and throughput to identify and quantify the chemical constituents of biosystems. Of the many available technologies, mass spectrometry is playing an increasingly important role in detection, identification and characterization of biological molecules. One major focus of our research is to develop enabling mass spectrometric tools for comprehensive proteome (the set of proteins that is or can be expressed by an organism) and metabolome.