Department of Medicine
University of British Columbia
Horacio Bach earned his PhD in Molecular Microbiology and Biotechnology from the University of Tel Aviv in 2001, studying the interactions between an esterase and the polysaccharide emulsan. Subsequently, in his first post-doctorate, he joined the laboratory of Prof. David Sherman in Minnesota working on the development of a biochip for generation of novel antibiotic molecules and the roles of P450 proteins from Streptomyces coelicolor. Dr. Bach worked for Taro Pharmaceuticals in Tel Aviv and New York developing novel fermentation technologies and engineering organisms for the production of steroids. In 2004, Dr. Bach joined the laboratory of Prof. at the Division of Infectious Diseases, Department of Medicine, University of British Columbia in Vancouver, Canada. He worked on the function of tyrosine phosphatases of Mycobacterium tuberculosis and the interactions within the host macrophages. Currently, Dr. Bach holds an Assistant Professor position at the same institution. His current research interests include: signal transduction, mechanism elucidation of virulence factors of Mycobacterium tuberculosis, the link between Mycobacterium paratuberculosis and inflammatory bowel diseases, the design of novel antibodies using antibody engineering, applications of nanotechnology in Medicine, and screening of novel bioactive natural compounds. Prof. Bach is the author of 40 papers, patents, reviews and book chapters.
Signal transduction, Mechanism elucidation of virulence factors of Mycobacterium tuberculosis, The link between Mycobacterium paratuberculosis and inflammatory bowel diseases, The design of novel antibodies using antibody engineering, Applications of nanotechnology in Medicine, Screening of novel bioactive natural compounds