Hannila, Sari
Assistant Professor
Anatomy and Cell Biology
Canada
Biography
A native of Sudbury, Ontario, Dr. Hannila received her Bachelor of Science degree in Life Sciences from Queen’s University. She then completed her PhD in the Department of Anatomy and Cell Biology at Queen’s University under the supervision of Dr. Michael Kawaja. Prior to joining the University of Manitoba, Dr. Hannila worked as a postdoctoral fellow in the laboratory of Dr. Marie T. Filbin at Hunter College in New York City. Her research focuses on the neurobiology of axonal regeneration in the central nervous system, with the goal of developing new treatments for spinal cord injury. She also studies the role of a protein called secretory leukocyte protease inhibitor in neural and vascular development.
Research Interest
Promoting axonal regeneration in the central nervous system (CNS) The CNS does not regenerate after injury, and this leads to permanent paralysis and sensory loss after spinal cord injuries
Publications
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Hannila SS, Filbin MT (2008) The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury. Exp. Neurol. 209:321-332
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Hannila SS, Siddiq MM, Filbin MT (2007) Therapeutic approaches to promoting axonal regeneration in the adult mammalian spinal cord. Int. Rev. Neurobiol. 77:57-105.
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Hannila SS, Siddiq MM, Carmel JB, Hou J, Chaudhry N, Bradley PMJ, Hilaire M, Richman EL, Hart RP, Filbin MT (2013) Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the TGFβ signaling protein Smad2. J. Neurosci. 33:5138-5151.