Jeffrey W. Keillor

Biography

Research conducted in the Keillor Lab can be divided into two areas. The first touches on several aspects of enzymology – studying the detailed mechanisms by which enzymes function, synthesizing and testing inhibitors with therapeutic potential, and engineering enzymes for practical catalytic applications. The second area involves the development of methods for labelling specific proteins in living cells, for the subsequent study of their structure, localisation and trafficking. The methodology used in the Keillor Lab for both of these two lines of research comprises several different disciplines, including organic synthesis, molecular biology and the spectroscopy implicated in detailed kinetic studies.

Research Interest

Physical and Theoretical Chemistry Organic and Biological Chemistry RMN Protein structures and membranes Protein structure and function Solution NMR Membrane proteins