Barry Linkletter
Associate Professor
Faculty of Sciences- Chemistry
University of Prince Edward Island
Canada
Biography
He did his Phd from McGill And now works aas Associate Professor in UPEI, Canada.
Research Interest
Dr. Barry Linkletter works to better understand and synthesize molecules that will interact and associate with four-stranded DNA, a novel DNA structure. These stabilizing molecules are candidates for drugs that regulate cell proliferation and may find a use in cancer therapy and genetic research.
Publications
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Bonneau R, Liu MT, Subramanian R, Linkletter B, Stevens ID. Benzylchlorocarbene: UV absorption spectrum, kinetics for 1, 2-H migration and mechanism for reaction with acetic acid as determined by combined continuous and laser-flash photolysis. Laser chemistry. 1990;10(5-6):267-75.
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Barawkar DA, Linkletter B, Bruice TC. Synthesis of protected guanidinium linked dinucleoside incorporable into an oligonucleotide using solid phase DNA methodology. Bioorganic & medicinal chemistry letters. 1998 Jun 16;8(12):1517-20.
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Wall M, Linkletter B, Williams D, Lebuis AM, Hynes RC, Chin J. Rapid Hydrolysis of 2 ‘, 3 ‘-cAMP with a Cu (II) Complex: Effect of Intramolecular Hydrogen Bonding on the Basicity and Reactivity of a Metal-Bound Hydroxide. Journal of the American Chemical Society. 1999 May 19;121(19):4710-1.
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Linkletter BA, Szabo IE, Bruice TC. Solid-phase synthesis of deoxynucleic guanidine (DNG) oligomers and melting point and circular dichroism analysis of binding fidelity of octameric thymidyl oligomers with DNA oligomers. Journal of the American Chemical Society. 1999 Apr 28;121(16):3888-96.
