Chris Eskiw
Assistant Professor
Food and Biproduct Sciences
University of Saskatchewan
Canada
Biography
Dr. Chris Eskiw, Currently, he is working as Assistant Professor, at University of Saskatchewan. His research interest includes that has been long been known that restricting nutrient/calorie intake promotes health and extends lifespan. However, the consequences of reduced nutrient uptake are not understood at the most basic level of our biology -- our genes. Understanding how our genes respond to nutrients is essential in order to design therapies/dietary strategies and to identify naturally occurring molecules found in foods to combat age-related disease and increase lifespan. The work in my laboratory aims to identify not only the genes involved in mediating health and longevity but also the mechanisms that drive this. Furthermore, my goal is to understand how nutrient availability and sensing impact genome folding, influencing in gene expression, leading to increased health and longevity.. He has authored several publications.
Research Interest
It has long been known that restricting nutrient/calorie intake promotes health and extends lifespan. However, the consequences of reduced nutrient uptake are not understood at the most basic level of our biology -- our genes. Understanding how our genes respond to nutrients is essential in order to design therapies/dietary strategies and to identify naturally occurring molecules found in foods to combat age-related disease and increase lifespan. The work in my laboratory aims to identify not only the genes involved in mediating health and longevity but also the mechanisms that drive this. Furthermore, my goal is to understand how nutrient availability and sensing impact genome folding, influencing in gene expression, leading to increased health and longevity.
Publications
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Cope NF, Fraser P, Eskiw CH. The yin and yang of chromatin spatial organization. Genome biology. 2010 Mar 29;11(3):204.
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Mehta IS, Eskiw CH, Arican HD, Kill IR, Bridger JM. Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells. Genome biology. 2011 Aug 12;12(8):R74.
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Eskiw CH, Fraser P. Ultrastructural study of transcription factories in mouse erythroblasts. J Cell Sci. 2011 Nov 1;124(21):3676-83.
