Valérie Legendre-guilleminubé
Associate Professor
Department of Biochemistry
University of Sherbrooke
Canada
Biography
Postdoctoral Studies: Boston, Harvard Medical School Joslin Diabetes Center PhD in Immunology in Marseille, University of the Mediterranean
Research Interest
Structural and functional analysis of the HIP1 and HIP1R proteins involved in clathrin mediated endocytosis
Publications
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Legendre-Guillemin V, Metzler M, Lemaire JF, Philie J, Gan L, Hayden MR, McPherson PS. Huntingtin interacting protein 1 (HIP1) regulates clathrin assembly through direct binding to the regulatory region of the clathrin light chain. Journal of Biological Chemistry. 2005 Feb 18;280(7):6101-8.
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Allaire PD, Ritter B, Thomas S, Burman JL, Denisov AY, Legendre-Guillemin V, Harper SQ, Davidson BL, Gehring K, McPherson PS. Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis. Journal of Neuroscience. 2006 Dec 20;26(51):13202-12.
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Ritter B, Denisov AY, Philie J, Allaire PD, Legendreâ€Guillemin V, Zylbergold P, Gehring K, McPherson PS. The NECAP PHear domain increases clathrin accessory protein binding potential. The EMBO journal. 2007 Sep 19;26(18):4066-77.
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Poupon V, Girard M, Legendre-Guillemin V, Thomas S, Bourbonniere L, Philie J, Bright NA, McPherson PS. Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly. Proceedings of the National Academy of Sciences. 2008 Jan 8;105(1):168-73.
