G. Angus Mcquibban
Associate Professor
Department of Biochemistry
University of Toronto
Canada
Biography
After completing an undergraduate degree and M.Sc. (Biochemistry) at the University of Toronto, he moved to Vancouver to pursue a Ph.D. (Biochemistry and Molecular Biology). his work focused on identifying novel substrates for a class of proteases (MMPs) that contribute to cancer metastasis. he discovered that inflammatory chemokines were a new family of substrates for this enzyme family. After completing my Ph.D. he moved to England for my PDF at the MRC-Laboratory of Molecular Biology in Cambridge. he continued his work of proteolysis, but this time working with a new family of proteases, called Rhomboids. There he revealed their important activity within mitochondria. he started my lab ‘back home’ in 2005, and since, his research interests have focused on mitochondrial quality control, and how dysregulation leads to human disease. his lab currently balances basic science projects with translational studies and small molecule screening to develop novel therapeutics in neurodegenerative disease.
Research Interest
Mitochondrial Quality Control Pathways and Human Neurodegenerative Disease
