Heyu Ni
Professor
Oncology
University of Toronto
Canada
Biography
Heyu Ni MD, PhD Professor Contact information Transfusion Medicine St. Michael's Hospital 30 Bond St. Rm 2006 B Wing Toronto Ontario M5B 1W8 Phone: 416-847-1738 Fax: 416-864-3060 Email: Nih@smh.ca Research location: St. Michael's Hospital/Research Institute Primary Research Area: Cardiovascular Secondary Research Area: Hematopathology Research Statement: We investigate the role(s) of adhesion molecules (in particular the beta3 integrin & GPIb alpha complexes) involved in clot formation & their implications for hemostasis (incl. bleeding disorders) & thrombotic diseases (ie heart attack & stroke). We study allo- & autoimmune diseases related to bleeding disorders such as immune thrombocytopenia (ITP) & fetal & neonatal alloimmune thrombocytopenic purpura (FNAIT). Heyu Ni MD, PhD Professor Contact information Transfusion Medicine St. Michael's Hospital 30 Bond St. Rm 2006 B Wing Toronto Ontario M5B 1W8 Phone: 416-847-1738 Fax: 416-864-3060 Email: Nih@smh.ca Research location: St. Michael's Hospital/Research Institute Primary Research Area: Cardiovascular Secondary Research Area: Hematopathology Research Statement: We investigate the role(s) of adhesion molecules (in particular the beta3 integrin & GPIb alpha complexes) involved in clot formation & their implications for hemostasis (incl. bleeding disorders) & thrombotic diseases (ie heart attack & stroke). We study allo- & autoimmune diseases related to bleeding disorders such as immune thrombocytopenia (ITP) & fetal & neonatal alloimmune thrombocytopenic purpura (FNAIT).
Research Interest
We investigate the role(s) of adhesion molecules (in particular the beta3 integrin & GPIb alpha complexes) involved in clot formation & their implications for hemostasis (incl. bleeding disorders) & thrombotic diseases (ie heart attack & stroke). We study allo- & autoimmune diseases related to bleeding disorders such as immune thrombocytopenia (ITP) & fetal & neonatal alloimmune thrombocytopenic purpura (FNAIT).
Publications
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Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H. Plasma fibronectin supports hemostasis and regulates thrombosis. J Clin Invest. 2014 Oct 1;124(10):4281-93.
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Jansen AJ, Peng J, Zhao HG, Hou M, Ni H. Sialidase inhibition to increase platelet counts: A new treatment option for thrombocytopenia. Am J Hemat. 2015 May;90(5):E94-5. 

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Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai WS, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen XY, Skogen B, Adamson SL, Freedman J, Ni H. Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage. J Clin Invest. 2015 Apr 1;125(4):1545-56.
