Michal Opas
Professor
Oncology
University of Toronto
Canada
Biography
Michal Opas MSc, PhD Professor Contact information Laboratory Medicine & Pathobiology University of Toronto 1 King's College Circle, Rm 6326 Toronto Ontario M5S 1A8 Phone: 416-971-2140 Fax: 416-978-5959 Email: m.opas@utoronto.ca Research location: University of Toronto - St. George Campus (downtown) Primary Research Area: Molecular & Cell Biology Secondary Research Area: Cardiovascular Research Statement: We study the role of calreticulin, a ubiquitous calcium-binding chaperone of the ER/SR, which affects calcium homeostasis and gene expression, in ES cell choice of fate. We discovered that calreticulin acts as a switch either promoting (bone) or suppressing (fat) stem cell differentiation, while it seems to deregulate cardiogenesis. Michal Opas MSc, PhD Professor Contact information Laboratory Medicine & Pathobiology University of Toronto 1 King's College Circle, Rm 6326 Toronto Ontario M5S 1A8 Phone: 416-971-2140 Fax: 416-978-5959 Email: m.opas@utoronto.ca Research location: University of Toronto - St. George Campus (downtown) Primary Research Area: Molecular & Cell Biology Secondary Research Area: Cardiovascular Research Statement: We study the role of calreticulin, a ubiquitous calcium-binding chaperone of the ER/SR, which affects calcium homeostasis and gene expression, in ES cell choice of fate. We discovered that calreticulin acts as a switch either promoting (bone) or suppressing (fat) stem cell differentiation, while it seems to deregulate cardiogenesis.
Research Interest
We study the role of calreticulin, a ubiquitous calcium-binding chaperone of the ER/SR, which affects calcium homeostasis and gene expression, in ES cell choice of fate. We discovered that calreticulin acts as a switch either promoting (bone) or suppressing (fat) stem cell differentiation, while it seems to deregulate cardiogenesis.
