Prosser, R. Scott
Professor
Department of Chemical & Physical Sciences
University of Toronto
Canada
Biography
Prosser, R. Scott is working as Professor in the Department of Chemical & Physical Sciences at the University of Toronto Mississauga
Research Interest
Our research focuses on dynamics and mechanism of complex biological processes such as: 1) protein folding, 2) Prosser Research Pictureprotein misfolding and amyloidosis, 3) enzyme functional dynamics, 4) GPCR functional dynamics, and 5) Direct molecular imaging of proteins and nanoparticles by MRI. In many cases, we make use of 19F or 13C,1H NMR to detect subtle low-lying states within an ensemble, and piece together a mechanistic description. 19F NMR chemical shifts are exquisitely sensitive to molecular environments. Thus, subtle differences in conformation, folding intermediates, or different aggregation states are more likely to be resolved by 19F NMR than by other methods.
