William S. Trimble
Professor
Department of Biochemistry
University of Toronto
Canada
Biography
Dr. Trimble received his Ph.D. in 1987 from the University of Toronto where he worked in the laboratory of Dr. Nobumichi Hozumi studying the mechanisms responsible for cellular transformation by the ras oncogene. He then went on to do postdoctoral work with Dr. Richard Scheller at Stanford University where he discovered the VAMP protein, the first member of the family of proteins now known as SNAREs that are responsible for the fusion of membranes in virtually all cellular contexts. In 1990 he moved back to the University of Toronto and in 1996 to the Hospital for Sick Children where he is a Senior Scientist and Head of the Cell Biology Program. His research focuses on the basic mechanisms controlling a variety of cellular processes, such as membrane transport, lipid metaobolism and cell division, and how these go awry in diseases such as atherosclerosis and cancer.
Research Interest
Membrane and Cytoskeleton Interaction
