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Andrew C. Doxey

Assistant Professor
Biology
University of Waterloo
Canada

Biography

Prof/Dr. Andrew Doxey is a bioinformatician with research interests in biological data mining, protein function prediction, and comparative and evolutionary genomics. The Doxey Lab develops computational methods to predict novel molecular or systems-level functions from genomes and other “omics” datasets. Current efforts are focused largely on uncharacterized proteins from newly sequenced microbial genomes and metagenomes. The Doxey Lab combines both “dry” (computational) and “wet” (biochemical/molecular) approaches, and works closely with a diverse range of local and international collaborators. PhD Bioinformatics, University of Waterloo, 2010. NSERC Postdoctoral Fellowship (PDF), 2010-2012. 2010 Governor General’s Gold Medal for top Ph.D., University of Waterloo. Member of International Society for Computational Biology, American Association for the Advancement of Science.

Research Interest

Bioinformatics Computational Biology Molecular Genetics

Publications

  • Broom A, Doxey AC, Lobsanov YD, Berthin LG, Rose DR, Howell PL, McConkey BJ, Meiering EM. Modular evolution and the origins of symmetry: reconstruction of a three-fold symmetric globular protein. Structure. 2012 Jan 11;20(1):161-71.

  • Yaish MW, Doxey AC, McConkey BJ, Moffatt BA, Griffith M. Cold-active winter rye glucanases with ice-binding capacity. Plant physiology. 2006 Aug 1;141(4):1459-72.

  • Doxey AC, Yaish MW, Griffith M, McConkey BJ. Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions. Nature biotechnology. 2006 Jul 1;24(7):852.

  • Doxey AC, Yaish MW, Moffatt BA, Griffith M, McConkey BJ. Functional divergence in the Arabidopsis β-1, 3-glucanase gene family inferred by phylogenetic reconstruction of expression states. Molecular biology and evolution. 2007 Feb 1;24(4):1045-55.

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