Forbes Burkowski
Professor
Cheriton School of Computer Science
University of Waterloo
Canada
Biography
Dr. Forbes Burkowski is a Professor in the Cheriton School of Computer Science, University of Waterloo, University Avenue West, Waterloo, ON, Canada.
Research Interest
Professor Burkowski is primarily interested in the mathematical models and computational algorithms that are related to structural bioinformatics. In biology, modeling the structure of a large molecule is very important if one is to understand its behaviour. Structure models have been utilized in the analysis of DNA, RNA, and proteins. In particular, proteins have a very complicated structure that allows them to interact with each other and with smaller molecules. The magic that is life takes place in the cavities of macromolecular surfaces. The primary area of research, for Dr. Burkowski, involves the geometric modeling of protein binding sites. A protein is a long chain-like molecule, typically involving thousands of atoms, and folded into a compact 'low energy' structure.
Publications
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Wong, W.W.L. and Burkowski, F.J., A constructive approach for discovering new drug leads: Using a kernel methodology for the inverse-QSAR problem, J. Cheminformatics, 2009, 1:4, 1-27
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Burkowski, F.J. and Wong, W.W.L, Predicting multiple binding modes using a kernel method based on a Vector Space Model Molecular Descriptor, Int. J. Computational Biology and Drug Design (IJCBDD), Vol. 2, No. 1, 2009. pp. 58-80.
