James W.e. Rush
Professor
Department of Kinesiology
University of Waterloo
Canada
Biography
Dr. James W.E. Rush is a professor in the Department of kinesiology, University of Waterloo, University Avenue West, Waterloo, ON, Canada.
Research Interest
Dr. James W.E. Rush research interests relate to regulation of blood vessel function and the signaling pathways in endothelial and vascular smooth muscle cells that control this function. In particular, I am interested in the effects of hypertension, age, and exercise on blood vessel health. Our recent work has focused on discovering regulatory influences on endothelium derived contracting factors, and on the effects of the red wine polyphenol resveratrol on vascular function. The ultimate goal of this research is to explain the mechanisms by which vascular function can be improved to prevent disease and the preserve cardiovascular health.
Publications
-
*Ford RJ, *Teschke SR, *Reid EB, *Durham KK, *Kroetsch JT, Rush JWE. AMP-activated protein kinase activator AICAR acutely lowers blood pressure and relaxes isolated resistance arteries of hypertensive rats. Journal of Hypertension, 30: 725-733, 2012.
-
*Denniss SG, * Ford RJ, * Smith CS, *Jeffery AJ, Rush, JWE. Chronic in vivo or acute in vitro resveratrol attenuates endothelium-dependent cyclooxygenase-mediated contractile signalling in hypertensive rat carotid artery. J Appl Physiol, 120: 1141-50, 2016
