Praveen Nekkar Rao
Associate Professor
Biology
University of Waterloo
Canada
Biography
"Dr. Nekkar Rao specializes in medicinal and bioorganic chemistry; exploring rational drug design aided by molecular modelling techniques and small molecule synthetic organic/medicinal chemistry. His work includes method development; solid phase peptide synthesis of bioactive peptides / peptidomimics; modern analytical techniques such as nuclear magnetic resonance spectroscopy, mass spectroscopy and high performance liquid chromatography; and development of high-throughput biochemical screening protocols to discover lead candidates."
Research Interest
Drug Discovery Rational Drug Design & Medicinal Chemistry Cancer Therapy Treatment of Neurodegenerative Disorders
Publications
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Tin G, Mohamed T, Gondora N, Beazely MA, Rao PP. Tricyclic phenothiazine and phenoselenazine derivatives as potential multi-targeting agents to treat Alzheimer's disease. MedChemComm. 2015;6(11):1930-41.
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Mohamed T, Shakeri A, Rao PP. Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry. European journal of medicinal chemistry. 2016 May 4;113:258-72.
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Mohamed T, Shakeri A, Tin G, Rao PP. Structure–activity relationship studies of isomeric 2, 4-diaminoquinazolines on β-amyloid aggregation kinetics. ACS medicinal chemistry letters. 2016 Mar 4;7(5):502-7.
