Trevor C. Charles
Professor
Biology
University of Waterloo
Canada
Biography
"Trevor C. Charles, 1991 PhD Biology, McMaster University, Hamilton, Ontario. Trevor Charles carries out research in bacterial genetics and is an expert on analyzing genetic material recovered directly from environmental samples, also known as functional metagenomics. In 2015, Prof. Charles was honoured with an Ontario Genomics Institute SPARK Award for an innovative project that uses waste methane to create renewable bioplastics. Professor Charles is a microbiologist with expertise in bacterial molecular genetics. His research group studies the mechanisms of gene regulatory circuits that control the interactions of Rhizobiales bacteria such as Sinorhizobium meliloti with their eukaryal hosts. The group also develops methods for functional metagenomics using alternate surrogate hosts, and employs these methods to isolate novel genes with interesting functions from microbial community genomic libraries. Current research emphasis is on functional metagenomics, bioplastics and bacterial genome engineering. 2015 Fellowship of Association of Biotechnology and Pharmacy (India). 2015 International Award of the Ninth DBN Science and Technology Awards (China). 2000-2010 President, Canadian Society of Microbiologists. "
Research Interest
"Plant-microbe interactions Symbiotic nitrogen fixation Functional metagenomics Bacterial genome engineering Synthetic biology, bioplastics and bioproducts"
Publications
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Yarosh OK, Charles TC, Finan TM. Analysis of C4â€dicarboxylate transport genes in Rhizobium meliloti. Molecular microbiology. 1989 Jun 1;3(6):813-23.
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Juck D, Charles T, Whyte LG, Greer C. Polyphasic microbial community analysis of petroleum hydrocarbon-contaminated soils from two northern Canadian communities. FEMS Microbiology Ecology. 2000 Sep 1;33(3):241-9.
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Li J, Ovakim DH, Charles TC, Glick BR. An ACC deaminase minus mutant of Enterobacter cloacae UW4No longer promotes root elongation. Current microbiology. 2000 Aug 21;41(2):101-5.
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Charles TC, Nester EW. A chromosomally encoded two-component sensory transduction system is required for virulence of Agrobacterium tumefaciens. Journal of bacteriology. 1993 Oct 1;175(20):6614-25.
