Dr. Arthur Brown
Associate Professor
Department of Medicine
University of Western Ontario
Canada
Biography
Dr. Arthur Brown is an Associate Professor in Department of Medicine at University of Western Ontario, Canada. Ph.D. The university of Toronto. Dr. Brown has combined his interests in neurological disease and neurodevelopment by initiating studies to address the role of embryonic genetic programs in regeneration and recovery from spinal cord injury. Dr. Brown has two major projects investigating therapeutic strategies to effect repair and regeneration after spinal cord injury. The first project is focused on manipulating gene expression in the injured spinal cord to up-regulate the expression of regeneration-promoting genes and to down-regulate the expression of regeneration-inhibiting genes.
Research Interest
Dr. Brown has combined his interests in neurological disease and neurodevelopment by initiating studies to address the role of embryonic genetic programs in regeneration and recovery from spinal cord injury. Dr. Brown has two major projects investigating therapeutic strategies to effect repair and regeneration after spinal cord injury. The first project is focused on manipulating gene expression in the injured spinal cord to up-regulate the expression of regeneration-promoting genes and to down-regulate the expression of regeneration-inhibiting genes.
Publications
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Stephen LJ, Fawkes AL, Verhoeve A, Lemke G, Brown A. A critical role for the EphA3 receptor tyrosine kinase in heart development. Developmental biology. 2007 Feb 1;302(1):66-79.
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Gris P, Tighe A, Levin D, Sharma R, Brown A. Transcriptional regulation of scar gene expression in primary astrocytes. Glia. 2007 Aug 15;55(11):1145-55.
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Brown A, Ricci MJ, Weaver LC. NGF mRNA is expressed in the dorsal root ganglia after spinal cord injury in the rat. Experimental neurology. 2007 May 31;205(1):283-6.
