Dr. Derek Mclachlin
Assistant Professor
Department of Biochemistry
University of Western Ontario
Canada
Biography
Dr. Derek McLachlin received Ph.D. University of Western Ontario, Post-doctoral Fellow, The Rockefeller University, Assistant Professor of Biochemistry at University of Western Ontario, Canada.
Research Interest
My PhD work was on the quaternary structure of E. coli ATP synthase, in particular the relationships between the two b subunits, and between these subunits and the rest of the complex. My postdoctoral studies focused on analysis of protein phosphorylation by mass spectrometry and chemical tools to selectively isolate phosphorylated peptides from complex mixtures. More recently I have become interested in the scholarship of teaching and learning.
Publications
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Csanády L, Seto-Young D, Chan KW, Cenciarelli C, Angel BB, Qin J, McLachlin DT, Krutchinsky AN, Chait BT, Nairn AC, Gadsby DC. Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA. The Journal of general physiology. 2005 Feb 1;125(2):171-86.
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Matsushita M, Kozak JA, Shimizu Y, McLachlin DT, Yamaguchi H, Wei FY, Tomizawa K, Matsui H, Chait BT, Cahalan MD, Nairn AC. Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. Journal of Biological Chemistry. 2005 May 27;280(21):20793-803.
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McLachlin DT. Song: I'll repair for you (To the tune of “I'll be there for you,†theme song for the television show,“Friendsâ€). Biochemistry and Molecular Biology Education. 2010 May 1;38(3):207-.
