Dr. Stephen Renaud
Assistant Professor
Department of Medicine
University of Western Ontario
Canada
Biography
Dr. Stephen Renaud is an Assistant Professor in Department of Medicine at University of Western Ontario, Canada. Ph.D. Queen's University
Research Interest
My research interests encompass the cellular and molecular mechanisms of placental development and function. There are two reasons I am interested in studying the placenta. First, the placenta is an exceptionally unique organ, one with evolutionary adaptations not observed in any other tissue. The second reason is from a public health perspective. The placenta intimately connects a mother with her developing baby, and it performs vital functions required for pregnancy such as regulating nutrient exchange between maternal and fetal blood, and producing hormones necessary for fetal development. Placental maldevelopment or dysfunction is linked with a variety of pregnancy complications (e.g. pre-eclampsia, fetal growth restriction, pre-term birth, placenta accreta, spontaneous abortion) that cause significant maternal and fetal illness or death. Despite its importance for the health of mothers and their babies, we really don’t have a good grasp on how the placenta develops or functions.
Publications
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Soares MJ, Chakraborty D, Rumi MK, Konno T, Renaud SJ. Rat placentation: an experimental model for investigating the hemochorial maternal-fetal interface. Placenta. 2012 Apr 30;33(4):233-43.
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Soares MJ, Chakraborty D, Renaud SJ, Kubota K, Bu P, Konno T, MA K. Regulatory pathways controlling the endovascular invasive trophoblast cell lineage. Journal of Reproduction and Development. 2012;58(3):283-7.
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Renaud SJ, Kubota K, Rumi MK, Soares MJ. The FOS transcription factor family differentially controls trophoblast migration and invasion. Journal of Biological Chemistry. 2014 Feb 21;289(8):5025-39.
