Jim Staples, Phd
Professor, Comparative Physiology and Biochemistry
Department of Biology
University of Western Ontario
Canada
Biography
Jim Staples, PhD Professor, Comparative Physiology and Biochemistry, of Department of Biology at the University of Western Ontario, Canada.
Research Interest
My research program aims to understand how the metabolic systems of animals adapt to environmental challenges. In particular I am interested in the strategies used by endothermic animals to deal with cold environments. When challenged by the cold, most endotherms increase metabolic rate and heat production. We study enzymatic and mitochondrial “futile cycles” in bumblebees and rats as possible mechanisms of non-shivering thermogenesis.
Publications
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Staples JF. Metabolic suppression in mammalian hibernation: the role of mitochondria. Journal of Experimental Biology. 2014 Jun 15;217(12):2032-6.
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Mathers KE, Staples JF. Saponin-permeabilization is not a viable alternative to isolated mitochondria for assessing oxidative metabolism in hibernation. Biology open. 2015 Jul 15;4(7):858-64.
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Staples JF. Metabolic flexibility: hibernation, torpor, and estivation. Comprehensive Physiology. 2016 Mar 15.