Liu Hong
Chemistry
China Pharmaceutical University
China
Biography
Liu Hong , female, the incumbent Chinese Academy of Sciences Shanghai Institute of Drug Research researcher, project leader, doctoral tutor . National Outstanding Young People, 100 Chinese Academy of Sciences Program, the eighth Chinese young female scientist winner. In 1999 graduated from the China Pharmaceutical University Department of Pharmaceutical Chemistry, received a doctorate in science; 1999 to 2001 in the Chinese Academy of Sciences Shanghai Institute of Drugs in postdoctoral research, after the stay. Respectively, in 2002 , 2005 in the United States of America The University of Texas Medical Branch at Galveston to visit the study and research work. Mainly engaged in medicinal chemistry, chemical biology and drug design research. In recent years, the "new drug lead discovery and optimization" of the main line, built a "new method of organic synthesis to promote drug discovery" new drug research technology system, mainly for infectious diseases, tumors, metabolic diseases and senile dementia and other major diseases In the study of new drug discovery, a number of candidate compounds with in-depth study value were found, and three compounds were undergoing a comprehensive preclinical study. Based on the dominant skeleton of drug molecules, a series of original innovative and efficient synthetic method systems have been developed, and a diversity of "dominant skeleton heterocycles" containing 6,000 molecules has been constructed . In Chemical Reviews , Angewandte Chemie International Edition ,Journal of Medicinal Chemistry , Chemistry & Biology , Organic Letters , Chemical Communications and Green Chemistry and other international academic journals published 260 papers, apply for 49 patents, access to invention patent certificate 13 , involved in the preparation of nine monographs.
Research Interest
Chemistry
Publications
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Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos A, Paus T, Evans AC, Rapoport JL. Brain development during childhood and adolescence: a longitudinal MRI study. Nature neuroscience. 1999 Oct 1;2(10):861-3.
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Simon C, Frati F, Beckenbach A, Crespi B, Liu H, Flook P. Evolution, weighting, and phylogenetic utility of mitochondrial gene sequences and a compilation of conserved polymerase chain reaction primers. Annals of the entomological Society of America. 1994 Nov 1;87(6):651-701.