Xu, Jinyi

Biography

Professor XU’s research focuses on the design and synthesis of novel cardiovascular drugs and studies on the structural modification and biological evaluation of natural products. She joined the cardiovascular drugs research group, involving in discovery non-peptide angiotensin II AT1 receptor antagonists and novel antihypertensive drugs. She also joined the antineoplastic agents research group, involving in the modification of anticancer compounds from plants and synthesis of novel derivatives of natural products, such as 23-hydroxy betulinic acid, 7,8-dihydroxy-3-methyl-isochromanone, oridonin,berberine, evodiamine,elemene and study on their biological activities, action of mechanisms as well as the structure activity relationships. She also joined the research group of novel anti-inflammatory agents, involving in the research and development of COX-2 inhibitors and dual cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) inhibitors as well as the related anti-tumor agents. Education 2001 Ph.D. Medicinal Chemistry China Pharmaceutical University 1991 M.S. Medicinal Chemistry China Pharmaceutical University 1986 B.S. Pharmacology China Pharmaceutical University Academic Experience 2006-      Professor of Department of Medicinal Chemistry Adviser of Ph. D.  

Research Interest

cardiovascular drugs and studies on the structural modification and biological evaluation of natural products.