Cai Jun
Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China
Biography
Dr. CAI Jun, Principal Investigator. Bachelor degree (Tsinghua University , 1999), PhD (Tsinghua University , 2005), Postdoctoral Research Fellow (University of Illinois at Urbana-Champaign, 2006-2008).
Research Interest
Our research group combines Computational biology and Genomics to investigate biological problems related to cancer genomics and stem cell genomics. The group is currently focusing on develop and use the single cell genome sequencing technology, to draw genomic variation map of somatic cells, thus to analyze the accumulation of genetic variation between healthy cell and in the evolutionary process from normal somatic cells into tumor cell.
Publications
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Yin S*, Yang J*, Lin B*, Deng W*, Zhang Y, Yi X, Shi Y, Tao Y,Cai J, Wu CI, Zhao G, Hurst L, Zhang J, Hu L§ and Kong X§, Exome sequencing identifies frequent mutation of MLL2 in non-small cell lung carcinoma from Chinese patients, Scientific Reports, 4, 6036, 2014
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Cai J, Miao X, Li Y, Cory Smith, Kitman Tsang, Cheng L, Wang Q, Whole-Genome Sequencing Identifies Genetic Variances in Culture-Expanded Human Mesenchymal Stem Cells, Stem cell reports, 3(2), 2014.
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Gao S*, Zheng C*, Chang G*, Liu W, Kou X, Tan K, Tao L, Xu K, Wang H, Cai J§, Tian JH§, Gao S§. Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cells. Nature Communications. 2015 Feb 18;6:6318.
