Chen Fei
Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China
Biography
Dr. CHEN is currently a professor in “100 talents program” of Chinese Academy of Sciences (CAS). He received his Ph.D. degree in biochemistry and molecular biology in 2003 from Jilin University. In 2005, he entered the University of Florida as a postdoctoral associate in the group of Dr Steven Benner. From 2006 to 2012, he worked as a research scientist, then a senior research scientist in the Foundation for Applied Molecular Evolution, Inc. His research interest is mainly focused on the structural and functional genomics of pathogens, as well as metagenomics. He has published number of peer-reviewed papers in scientific journals including “PNAS”, “JACS”, and “Nucleic Acid Res”, and also jointly owned three patents.
Research Interest
Dr. CHEN’s research mainly focuses on precision genomics, including precision genome and epigenome characterization of pathogenic microorganisms (such as Mycobacterium tuberculosis, Klebsiella Pneumoniae, Pseudomonas aeruginosa and other important pathogens), metagenomics and cancer genomics. Besides, based on quick and accurate technology to detect nucleic acid in clinical samples, we are developing differential diagnosis kit for HIV drug-resistant genotype and various respiratory pathogens.
Publications
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Yang Z#, Chen F#, Brian JA, Benner SA. Amplification, Mutation, and Sequencing of a Six-Letter Synthetic Genetic System. J Am Chem Soc. 2011. 133: 15105-12. (#Co-First Author)
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Chen F, Yang Z, Yan M, Brian JA, Wang GG, Benner SA. Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity. Nucleic Acid Res. 2011. 39: 3949-61.
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Zhu L#, Zhong J#, Jia X#, Liu G#, Kang Y#, Dong M, Zhang X, Li Q, Yue L, Li C, Fu J, Xiao J, Yan J, Zhang B, Lei M, Chen S, Lv L, Zhu B, Huang H*, Chen F*. Precision methylome characterization of Mycobacterium tuberculosis complex (MTBC) using PacBio Single-Molecule Real-Time (SMRT) Technology. Nucleic Acids Research. 2016. 44(2): 730-743. (*Corresponding Author)
