Chen Jilong
Professor
Institute of Microbiology
Chinese Academy of Sciences
China
Biography
Postdoc University of Iowa, USA, Molecular Biology and Genetics 1994-1998 Ph.D. Peking University, China Molecular Cell Biology 1992 Prof. Chen received Ph.D. in Molecular Cell Biology from Peking University in 1992. He worked as a post-doctoral research fellow at University of Iowa during 1994-1998. He has worked at Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (CAS) as an associate professor (1998-1999) and then professor (2000). He worked as a senior visiting scholar and research scientist at University of Iowa (2000-2008). He joined Institute of Microbiolgy, CAS as a professor supported by “one hundred talents program” since 2008. His research works have been published in Blood, J. Cell Biol., PNAS, Nature Chemical Biology, Nature Cell Biology, J. Biol. Chem，Oncogene, Neoplasia and so on.
Research Interest
1. Molecular mechanisms of Abl oncogenes-mediated tumorigenesis. 2. Regulation of cytokine signaling by virus infection. 3. Signaling pathways of T cell activation and Signal transduction pathways in antiviral immunity 4. Role of long non-coding RNA (lncRNA) in virus infection and tumorigenesis. 5. Key roles of small GTPases in intracellular protein transport, virus infection and cellular transformation.
Publications
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[3] Jing Ouyang, Jiayue Hu and Ji-Long Chen*. lncRNAs regulate the innate immune response to viral infection. Wiley Interdiscip Rev RNA (WIREs RNA). 2016;7(1):129-143.
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[2] Ke Chen, Jianling Yang, Jianning Li, Xuefei Wang, Yuhai Chen, Shile Huang, Ji-Long Chen*. eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants. Oncotarget, 2016 ; doi: 10.18632/oncotarget.7164.
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[1] Fang Li, Yuhai Chen, Zhaoyuan Zhang, Jing Ouyang, Yi Wang, Ruoxiang Yan, Shile Huang, George Fu Gao, Guijie Guo and Ji-Long Chen*. Robust expression of vault RNAs induced by influenza A virus plays a critical role in suppression of PKR-mediated innate immunity. Nucleic Acids Research, 2015 ;43(21):10321-10337. (*通讯作者，下åŒ)
