Ci Weimin
Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China
Biography
Dr. CI is currently a professor of Beijing Institute of Genomics, Chinese Academy of Sciences (CAS). She got her PhD from Institute of Biophysics, CAS in 2004. And from 2004 to 2009, she got her Postdoc training in Albert Einstein College of Medicine and Cornell Medical College, respectively. Then, she joined Beijing Institute of Genomics at 2009.
Research Interest
Dr. CI's current research focuses on DNA methylation reprogramming in tissue-specific cell differentiation and tumorigenesis. The ultimate goal of my laboratory is to define the DNA methylation changes that occur in cancers especially renal cell carcinomas, to discover the molecular causes of these changes, and to translate that newly gained knowledge into the clinic in the form of novel, epigenetic-based therapies. A wide spectrum of experimental approaches will be employed, including molecular and cellular biology, biochemistry, genomics and proteomics.
Publications
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Ke CHEN#, Jing ZHANG#, Zhongqiang GUO#, Qin MA, Zhengzheng XU, Yuanyuan ZHOU, Ziying XU, Zhongwu LI, Yiqiang LIU, Xiongjun YE, Xuesong LI, Bifeng YUAN, Yuwen KE, Chuan HE, Liqun ZHOU*, Jiang LIU*, and Weimin CI*. Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer, Cell Research, 2016, 26(1):103-118.
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Ester VALLS, Camille LOBYR, Huimin GENG, Ling WANG, Mariano CARDENAS, MartÃn RIVAS, Leandro CERCHIETTI, Philmo OH, Shao Ning YANG, Erin OSWALD, Camille W. GRAHAM, Yanwen JIANG, Katerina HATZI, Xabi AGUIRRE, Eric PERKEY, Zhuoning LI, Wayne TAM, Kamala BHATT, Spyros Artavanis-Tsakonas, John P. LEONARD, Patrick A. Zweidler-McKay, Ivan MAILLARD, Olivier ELEMENTO, Weimin CI*, Iannis AIFABTIS* and Ari MELNICK*. BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells, Cancer Discovery, 2017, 7(5):506-521.
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Qin MA, Huan LU, Ziying XU, Yuanyuan ZHOU & Weimin CI*. Mouse olfactory bulb methylome andhydroxymethylome maps reveal noncanonical active turnover of DNA methylation, Epigenetics, 2017, 12(8):708-714
