Jiangyun Wang

Biography

2007-current Professor, Institute of Biophysics, Chinese Academy of Sciences 2003-2007 Postdoctoral training, Dept. of Chemistry (Advisor: Prof. Peter G. Schultz) The Scripps Research Institute 1998-2003 Ph.D., Dept. of Chemistry (Advisor: Prof. Kenneth S. Suslick) Univ. of Illinois at Urbana-Champaign 1994-1998 B.S., Dept. of Special Class for Gifted Young (Advisor: Prof. Zuyao Chen) Univ. of Science and Technology of China 2007-current Professor, Institute of Biophysics, Chinese Academy of Sciences 2003-2007 Postdoctoral training, Dept. of Chemistry (Advisor: Prof. Peter G. Schultz) The Scripps Research Institute 1998-2003 Ph.D., Dept. of Chemistry (Advisor: Prof. Kenneth S. Suslick) Univ. of Illinois at Urbana-Champaign 1994-1998 B.S., Dept. of Special Class for Gifted Young (Advisor: Prof. Zuyao Chen) Univ. of Science and Technology of China

Research Interest

Metalloenzymes catalyze some of the most challenging reactions, such as the conversion of H2O to O2, O2 to H2O, N2 to NH3 and H+ to H2, under mild physiological conditions. As these reactions are of tremendous importance for energy production and green chemistry, they are currently intensively investigated by biophysical chemists. However, these metalloenzymes are usually huge membrane protein complexes, and are hard to produce in large amount for performing biochemical studies, and are difficult to engineer to suit for industrial applications. The central aim in our laboratory is to use small, soluble protein scaffold, and the genetic incorporation of unnatural amino acid to design easy-to-characterize, easy-to-produce, and easy-to-optimize metalloenzymes which catalyze these important reactions with equal or greater efficiency/selectivity than that of the natural systems.