Kongjiang Wang

Biography

1992.09-1995.07   Technical Physics Department, Radiation Chem., Peking University, PH, D 1995.08-1997.07   Nuclear Analysis Department, Institute of High Energy Physics, Chinese Academy of Sciences, Postdoc. fellow 1997.08-1998.12　Nuclear Analysis Department,Institute of High Energy Physics, Chinese Academy of Sciences, Assistant Prof. 1999.01-2002.06　Department of Chemistry, NSCORT, Rensselaer Polytechnic Institute, Troy, NY12170, New York, USA, Postdoc. fellow 2002.07 - Now　 Institute of Biophysics, Chinese Academy of Sciences, Prof., PI (Biotech.) 1992.09-1995.07   Technical Physics Department, Radiation Chem., Peking University, PH, D 1995.08-1997.07   Nuclear Analysis Department, Institute of High Energy Physics, Chinese Academy of Sciences, Postdoc. fellow 1997.08-1998.12　Nuclear Analysis Department,Institute of High Energy Physics, Chinese Academy of Sciences, Assistant Prof. 1999.01-2002.06　Department of Chemistry, NSCORT, Rensselaer Polytechnic Institute, Troy, NY12170, New York, USA, Postdoc. fellow 2002.07 - Now　 Institute of Biophysics, Chinese Academy of Sciences, Prof., PI (Biotech.)

Research Interest

1. Topics related to the origins of life In our simulation of the photochemical processes related to the origins of life, we found the energy transfer from UV-excited phosphate radicals to nucleic acid monomers and the enhanced photolysis of nucleic acid monomers（Wang* KJ, Pan XM., Wu JL & Wang WQ., Photochem. Photobiol., 65: 656-659, 1997; Wang* KJ, Chai ZF & Pan XM., Origins Life Evol. Biosph. 29: 261-272, 1999）. This is an additional pathway of photolysis of nucleic acids. In our probe to the origin of bio-chirality, we found the highly efficient longer peptide formation enhanced by the most common simple ions like Na+ and Cl-（Jie Ren, Liang Xin, Yi-Nan Liu, Kong-Jiang Wang*, Macromolecules, 41(6): 1996-2002, 2008; Xin L.; Ma YL.; Liu YN., Yan Q.; Wang* KJ, Biopolymers 81: 1-7, 2006; Wang* KJ, 3：Yao N., Li C., Origins Life Evol. Biosph., 2005, 35: 313-322; Liu Y. N. Wang* K. J., Origins Life Evol. Biosph., 2006, 36: 321-322）. For reviews , please refer to following papers (王孔江*, 辛亮, 任洁,化学进展, 18(10): 1391-1396, 2006; Wang* KJ, Ren J., Xin L., in “Progress in Biopolymer Research”, ed., by Pablo C. Sanchez (University of Michigan, Ann Arbor, Michigan, USA), 2008, pp. 3-7). We also reported: 1) The photoinduced reduction of thymine and uracil derivatives by hypophosphite（Wang* KJ & Chai ZF., Chem. Commun., 1543-1544, 1998.）；2) An new intermediate in the polymerization of arginine and the proposed mechanism of arginine polymerization (Liang Xin, Jun-Feng Xiang, Jie Ren, Kong-Jiang Wang*, Sci.China Ser. B-Chem.,52(8): 1220-1226, 2009). The methods for both the HPLC analysis of oligopeptides of L-glutamic acid and L-arginine（Wang* KJ & Nai P., Li SS., Anal. Biochem., 332: 199-201, 2004.) and the accurate determination of dehydration methods of uracil hydrate derivatives（Wang* KJ & Chai ZF., J. Photochem. Photobiol., A: Chemistry 109: 143-146, 1997.) are also established. During my postdoctor research in Prof. James P. Ferris laboratory (NSCORT), I got involved in the montmorillnite-catalyzed RNA synthesis (Wang KJ, Ferris* JP., Origins Life Evol. Biosph., 2005, 35: 187-212； Ferris* JP, Joshi PC, Wang KJ, Miyakawa S, Huang W., Adv. Space Res., 33:100-105, 2004.)