Li Huang
Professor
Department of Biology
Chinese Academy of Sciences
China
Biography
Professor Huang received his PhD in the Department ofMicrobiology at the University of Guelph, Ontario, Canada, in 1988. He was a postdoctoral fellow in the Department of Biochemistry of the School of Hygiene and Public Health at Johns Hopkins University, Maryland, from 1988 to 1993. He became assistant professor in the Department of Biology at Pomona College, California, in 1993 before joining the faculty in the Institute of Microbiology, Chinese Academy of Sciences, in 1996. He was appointed to full professorship in 1998 and had been director of the State Key Laboratory of Microbial Resources from 2000 to 2008. He served as the Deputy Director and then Director of the Institute of Microbiology, Chinese Academy of Sciences, in April 2008 to September 2013.
Research Interest
Dr. Huang’s laboratory studies chromosomal organization and DNA replication in the hyperthermophilic archaea of the genus Sulfolobus. The following projects are currently ongoing in his laboratory. DNA-binding proteins Sul7d and Cren7 from Sulfolobus and their roles in chromosomal organization Biochemical properties and physiological function of the highly conserved Sac10b protein family Key steps in DNA replication in Sulfolobus solfataricus Sulfolobus viruses from hot springs in Yunnan and Tibet
Publications
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Likui Zhang, HuiqiangLou, Li Guo, Zhengyan Zhan, Zhenhong Duan, Xin Guo and Li Huang*. 2010. Accurate DNA synthesis by Sulfolobus solfataricus DNA polymerase B1 at high temperature. Extremophiles, 14(1):107-17. (IF 1.782)
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Xin Guo and Li Huang*. 2010. An SF3 DNA helicase encoded by plasmid pSSVi from the hyperthermophilic Archaeon Sulfolobus solfataricus unwinds DNA as a higher-order oligomer and interacts with host primase. The Journal of Bacteriology, 192(7):1853-64. (IF 3.636)
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Zhenfeng Zhang#, Yong Gong#, Li Guo, Tao Jiang, Li Huang*. Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA. Molecular Microbiology. In press. (# shared the first author) (IF 5.213)
