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Molecular Biology Experts

Li Mingkun

Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China

Biography

Dr. LI is a professor and principal investigator at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences (CAS). Dr. LI received the B.S. and M.S. degrees in Biology from Northwest A & F University, Shannxi, China in 2006. He received a Ph.D. in Bioinformatics/Genetics from Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany in July 2012 (advisor: Dr. Mark Stoneking), and did postdoctoral research in the same lab until Oct 2013. He held a position as Senior Scientist/Bioinformatics Group leader at Fondation Merieux, Lyon, France before joining BIG. Dr. LI's expertise is bioinformatics, metagenomics, and molecular evolution.  

Research Interest

1. lung microbiome   2. Mitochondrial DNA 3. Human mtDNA genomics and population genetics

Publications

  • Wachsmuth M, Huebner A, Li MK, Madea B, Stoneking M. 2016. Age-related and heteroplasmy-related variation in human mtDNA copy number. Plos Genet, 12(3): e1005939

  • Li MK, Schroeder R, Ni SY, Madea B, Stoneking M. 2015. Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations. PNAS. 112(8):2491-6

  • Li MK, Rothwell R, Vermaat M, Wachsmuth Manja, Schroder R, et al. Genome of the Netherlands Consortium. 2016. Transmission of human mtDNA heteroplasmy in the genome of the Netherlands families: support for a variable-size bottleneck. Genome Research, 10.1101/gr.203216.115

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