Lijun Bi
Institute of Biophysics
Chinese Academy of Sciences
China
Biography
1997-2000: MSc, Shenyang Agricultural University, China. Purification of polyphenol oxidase from Nanguo pear. 2000-2003: PhD, Wuhan Institute of Virology, Chinese Academy of Sciences. Development of microarrays for detecting drug resistance in M. tuberculosis. 2003-2004: Postdoctoral Research, Kinki University, Japan. Quantitative proteomics of transgenic mammal single cells. 2004-present: Principal Investigator, CAS Institute of Biophysics. DNA repair mechanisms and systems biology of M. tuberculosis. 2011: Visiting Professor in the laboratory of Prof. John Chan, Department of Microbiology and Immunology, Einstein Institute of Medicine, New York, USA. M. tuberculosis infection and host immunology. 1997-2000: MSc, Shenyang Agricultural University, China. Purification of polyphenol oxidase from Nanguo pear. 2000-2003: PhD, Wuhan Institute of Virology, Chinese Academy of Sciences. Development of microarrays for detecting drug resistance in M. tuberculosis. 2003-2004: Postdoctoral Research, Kinki University, Japan. Quantitative proteomics of transgenic mammal single cells. 2004-present: Principal Investigator, CAS Institute of Biophysics. DNA repair mechanisms and systems biology of M. tuberculosis. 2011: Visiting Professor in the laboratory of Prof. John Chan, Department of Microbiology and Immunology, Einstein Institute of Medicine, New York, USA. M. tuberculosis infection and host immunology.
Research Interest
Prof Bi’s work focuses on problems encountered in the diagnosis and treatment of tuberculosis, including the poor detection rate of TB, the rise of drug resistance, the poor protection afforded by current vaccines, and the lack of drugs for treating latent TB infections. Her network of research collaborations spans different disciplines within IBP and different institutes and universities, both nationally and internationally. Using the concepts of systems biomedicine, her group has developed new research methods and techniques and identified new biomarkers, immunogens and drug targets. These results and achievements have been published in more than 80 papers in international journals including Nature Genetics, Cell Research, and Nucleic Acids Research. The group also has 10 patents.
Publications
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Zheng P, Xiong Q, Wu Y, Chen Y, Chen Z, Fleming J, Gao D, Bi L*, Ge F. Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells. Mol Cell Proteomics, 2015, 14:1447-63.