Liu Xin
Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China
Biography
Dr. LIU Xin is currently a professor at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences (CAS). She also serves as an adjunct assistant professor in the Department of Pediatrics, Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Dr. LIU received a bachelor’s degree in clinical medicine from Shandong Medical University, China in 1993, and a Ph.D. in genetic epidemiology from Johns Hopkins University Bloomberg School of Public Health (JHBSPH), Baltimore, Maryland, USA, in 2002 (thesis advisor: Dr. Terri H Beaty). Dr. LIU pursued her postdoctoral training in the Department of Epidemiology at JHBSPH under the supervision of Dr. Margaret Daniele Fallin, and then in the Department of Epidemiology and Biostatistics at the University of California at San Francisco under the supervision of Dr. John S. Witte. Before joining the faculty at Beijing Institute of Genomics, Dr. LIU was an Assistant Professor in the Department of Pediatrics (2007-2015) and Preventive Medicine (2011-2015), at Northwestern University Feinberg School of Medicine. Dr. LIU Xin has extensive experience in genetic epidemiological studies of complex diseases, including prostate cancer and childhood diseases. She has authored and co-authored ~60 publications in peer-reviewed scientific journals. Dr. LIU was the PI (R03 AI105294, R21AI087888) and co-investigator of several NIH-funded large-scale genetic epidemiological studies of food allergy, preterm birth and obesity.
Research Interest
Our group is interested in the genetic epidemiological study of complex traits/diseases and pharmacogenetics, specifically in: (1) Identifying genetic variants, epigenetic alterations, and other biomarkers for disease risk and progression; and (2) Engaging in pharmacogenetic studies to determine genetic and epigenetic factors in medication responses. The overall goal of our research program is to assess and predict disease risk and therapeutic response for complex diseases, such as leukemiaã€hemophagocytic lymphohistiocytosis (HLH) and obesity-related diseases.
Publications
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Liu X, Beaty TH, Deindl P, Huang SK, Lau S, Sommerfeld C, Fallin D, Kao WH, Wahn U, Nickel R. Association between specific serum IgE response and 6 variants within genes IL4, IL13 and IL4Rα in German Children: the German Multicenter Atopy Study (MAS). The Journal of Allergy and Clinical Immunology 2004;113:489-95.
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Liu X, Beaty TH, Deindl P, Huang SK, Lau S, Sommerfeld C, Fallin D, Kao WH, Wahn U, Nickel R. Association between total serum IgE levels and the six potentially functional variants within genes IL4, IL13 and IL4Rα in German Children: the German Multicenter Atopy Study (MAS). The Journal of Allergy and Clinical Immunology 2003:112:382-388.
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Liu X, Nickel R, Beyer K, Wahn U, Ehrlich E, Freidhoff LR, Björkstén B, Beaty TH, Huang SK and the MAS-Study Group. An IL13 coding region variant is associated with high total serum IgE level and atopic dermatitis in German Multicenter Atopy Study (MAS-90). The Journal of Allergy and Clinical Immunology 2000;106:167-170.
