Lu Xuemei
Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China
Biography
Dr. LU Xuemei is a professor of Beijing Institute of Genomics, Chinese Academy of Sciences. Dr. LU started scientific career since 1997 when she received her Master degree from the South China Agricultural University. After 3-years professional training at the State Key Laboratory of Molecular Genetics and Evolution, in the Kunming Institute of Zoology in CAS, Dr. LU received her Ph.D. degree in Molecular Evolution in 2001. Dr. LU continued her postdoctoral research in the Center for Reproduction of Endangered Species, Zoological Society of San Diego from 2001 to 2002; and in the Department of Ecology and Evolution in the University of Chicago from 2003 to 2005. She was recruited to be an Associate Professor by School of Life Science, Sun Yet-Sen University in 2006 and promoted to Professor in Beijing Institute of Genomics in 2009. Dr. LU’s lab is currently focusing on genomic variations and evolution of complex traits and cancers.
Research Interest
Dr. LU’s lab focuses on evolutionary genomics of complex traits and cancer in human and animal model systems using genomic and population genetic approaches. Our current research interests are in addressing 1) the evolutionary process and diversity within and between cellular populations/tumors, 2) evolution of complex traits and artificial selection in animals, and 3) evolution of gene regulatory in cells and polyploidy animal species by analyzing genomic, epigenomic and transcriptional variations.
Publications
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Yong Tao#, Zheng Hu#, Shaoping Ling#, Shiou-Hwie Yeh, Weiwei Zhai, Ke Chen, Chunyan Li, Yu Wang, Kaile Wang, Hurng-Yi Wang, Eric A Hungate, Kenan Onel, Jiang Liu, Changqing Zeng, Richard R Hudson, Pei-Jer Chen, Xuemei Lu*, Chung-I Wu* Further genetic diversification in multiple tumors and an evolutionary perspective on therapeutics. 2015, bioRxiv doi: http://dx.doi.org/10.1101/025429
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Guojing Liu#, Rui Zhang#, Jin Xu, Chung-I Wu* and Xuemei Lu*. Functional conservation of both CDS- and 3’UTR- located miRNA binding sites between species. Molecular biology and evolution, 2015, 32(3): 623-628
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Shaoping Ling#, Zheng Hu#, Zuyu Yang#, Yang, Fang#, Yawei Li, Pei Lin, Ke Chen, Lili Dong, Lihua Cao, Yong Tao, Lingtong Hao, Qingjian Chen, Qiang Gong, Dafei Wu, Wenjie Li, Wenming Zhao, Xiuyun Tian, Chunyi Hao*,Eric A. Hungate, Daniel V. T. Catenacci, Richard R. Hudson, Wen-Hsiung Li*, Xuemei Lu*, Chung-I Wu*, Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution,Proceedings of the National Academy of Sciences of the United States of America, 2015, 112(47):E6496-E6505