Shaohui Huang

Biography

Professional Experience: 1988-1991 Undergraduate study in Biochemistry, Sun Yat-sen University, Guangzhou, China 1991-1993 B.S. in Biochemistry, Department of Molecular Biosciences, the University of Kansas, Lawrence, Kansas 1993 -1998 Ph.D. in Biochemistry, Molecular & Cell Biology, Department of Molecular Biosciences， the University of Kansas, Lawrence, Kansas 1998-2002 Postdoctor, School of Applied and Engineering Physics, Cornell University, Ithaca, New York 2002-2009 Research Assistant Professor, Program in Molecular Medicine, the University of Massachusetts Medical School, Worcester, Massachusetts 2009-2013 Investigator, Institute for Environmental Medicine (IFEM), the University of Pennsylvania School of Medicine, Philadelphia, PA 2009-2013 Director, IFEM Pulmonary Imaging and Morphology Core, the University of Pennsylvania School of Medicine, Philadelphia, PA 2010-2013 Research Assistant Professor, Department of Physiology, the University of Pennsylvania, Philadelphia, PA 2013-present Principal Investigator，Center for Interdisciplinary Study, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China Professional Experience: 1988-1991 Undergraduate study in Biochemistry, Sun Yat-sen University, Guangzhou, China 1991-1993 B.S. in Biochemistry, Department of Molecular Biosciences, the University of Kansas, Lawrence, Kansas 1993 -1998 Ph.D. in Biochemistry, Molecular & Cell Biology, Department of Molecular Biosciences， the University of Kansas, Lawrence, Kansas 1998-2002 Postdoctor, School of Applied and Engineering Physics, Cornell University, Ithaca, New York 2002-2009 Research Assistant Professor, Program in Molecular Medicine, the University of Massachusetts Medical School, Worcester, Massachusetts 2009-2013 Investigator, Institute for Environmental Medicine (IFEM), the University of Pennsylvania School of Medicine, Philadelphia, PA 2009-2013 Director, IFEM Pulmonary Imaging and Morphology Core, the University of Pennsylvania School of Medicine, Philadelphia, PA 2010-2013 Research Assistant Professor, Department of Physiology, the University of Pennsylvania, Philadelphia, PA 2013-present Principal Investigator，Center for Interdisciplinary Study, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

Research Interest

1) Instrument development : our team developed a portable, ultrasensitive molecular analyzer based on fluorescence correlation spectroscopy principles. We have also built an advanced single-molecule research platform integrating multiparameter fluorescence detection and atomic force microscopy techniques. 2) Molecular mechanism of organelle biogenesis: we are investigating the molecular mechanism of giant lamellar bodies (GLBs) in the alveolar type II pneumocyte. Lung fibrosis related to GLB is the fatal cause of Hermansky-Pudlak Syndrome patients.