Shengdian Wang
Institute of Biophysics
Chinese Academy of Sciences
China
Biography
1998: Ph.D., Chinese Academic Medical Science/Beijing Union Medical College; 1998-2004: Postdoctoral fellow/ Research Associate, Department of Immunology, Mayo Medical School, Mayo Clinic, USA; 2004~2005: Research Associate, Johns Hopkins University School of Medicine, USA 2005-present: Professor, Institute of Biophysics, Chinese Academy of Sciences. 1998: Ph.D., Chinese Academic Medical Science/Beijing Union Medical College; 1998-2004: Postdoctoral fellow/ Research Associate, Department of Immunology, Mayo Medical School, Mayo Clinic, USA; 2004~2005: Research Associate, Johns Hopkins University School of Medicine, USA 2005-present: Professor, Institute of Biophysics, Chinese Academy of Sciences.
Research Interest
Our past studies made significant contributions to determining the critical role of immune system in antitumor effects of conventional cancer treatments. At present, we focus on the molecular and cellular mechanisms of antitumor immune responses and immune suppression in tumor microenvironment to identify the dominant immunosuppressive components that inhibit tumor-specific T cell responses. We are also interested in molecular mechanisms of memory T cell differentiation and function, which is important for controlling tumor recurrence. These studies will shed light on improvement of conventional cancer treatments and development of new tumor immunotherapies.
Publications
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Li X, Wang P, Li H, Du X, Liu M, Huang Q, Wang Y, Wang S*. The efficacy of oncolytic adenovirus is mediatedby T cell responses against virus and tumor in Syrian hamster model. Clin Cancer Res. 2017 Jan 1;23(1):239-249.
