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Bioinformatics & Systems Biology Experts

Tao Jiang


Institute of Biophysics
Chinese Academy of Sciences
China

Biography

1987-1991 Bachelor of Chemistry, Xiamen University , 1995-1998 PhD. of Biophysics, Institute of Biophysics, CAS 1999-2004 Associate professor, Institute of Biophysics, CAS 2004-present Professor, Institute of Biophysics, CAS 2009- Millions of Leading Engineering Talents 2010- 3th ‘Tan Jiazhen Life Science Innovation Award ’ 2010- National Science Fund for Distinguished Young Scholars 2010- "Excellence Award" of "The 100 Talents" program by Chinese Academy of Sciences 2014- Ten Thousand Talent Program-Young and middle-aged leading scientists, engineers and innovators 1987-1991 Bachelor of Chemistry, Xiamen University , 1995-1998 PhD. of Biophysics, Institute of Biophysics, CAS 1999-2004 Associate professor, Institute of Biophysics, CAS 2004-present Professor, Institute of Biophysics, CAS 2009- Millions of Leading Engineering Talents 2010- 3th ‘Tan Jiazhen Life Science Innovation Award ’ 2010- National Science Fund for Distinguished Young Scholars 2010- "Excellence Award" of "The 100 Talents" program by Chinese Academy of Sciences 2014- Ten Thousand Talent Program-Young and middle-aged leading scientists, engineers and innovators

Research Interest

In recent years, our group is concentrating on structural and functional analysis of biomacromolecules by use of structural biology approaches, with particular emphasis on the following aspects: Our overall research goal is to determine the 3D-structure of these proteins, in conjugation with functional studies to decipher their molecular mechanisms and provide structure basis for the drug development for neurodegenerative diseases, cancer and metabolic disorders. (1) Neurotrophin and neurotrophin receptors, which play essential role in the survival, differentiation and maintenance of different peripheral and central neurons. (2) DNA damage responses proteins and protein complexes, which functions coordinately to maintain genomic stability and ensure cellular survival. (3) Membrane transporters, which facilitate the transport of metabolic intermediates between cell compartments as well as into and out of the cell.

Publications

  • Wang T. Y., Sun H. L., Cheng F., Zhang X. E, Bi L. J. *, Jiang T. * (2013) Recognition and processing of double-stranded DNA by ExoX, a distributive 3’–5’ exonuclease. Nucleic Acids Res, 41 (15): 7556-7565.

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