Yan Li
Institute of Biophysics
Chinese Academy of Sciences
China
Biography
1994-1998 BS in Department of Pharmacy, Peking University Healthy Science Center 2000-2004 PhD in Department of Chemistry and Biochemistry, University of Maryland 2004 -2005 Research Scientist inCalibrant Biosystems Inc. 2005-2011 Research fellow/Research Associate in Department of Pathology, Johns Hopkins University 2011-presentPrincipal Investigator in CAS Institute of Biophysics 1994-1998 BS in Department of Pharmacy, Peking University Healthy Science Center 2000-2004 PhD in Department of Chemistry and Biochemistry, University of Maryland 2004 -2005 Research Scientist inCalibrant Biosystems Inc. 2005-2011 Research fellow/Research Associate in Department of Pathology, Johns Hopkins University 2011-presentPrincipal Investigator in CAS Institute of Biophysics
Research Interest
Protein modification is one of the significant mechanisms of protein function and disease progression. Our research interests focus on determining protein modifications associated with disease, especially for glycoproteins and their glycosylation. These include: the development of new technologies for low-abundance proteom and glycan analyses; discovery and verify disease biomarkers using high throughput approaches of clinical proteomics and glycomics.The aim of our researches is to provide a greater understanding of human proteome and glycans in the diagnosis and management of human disease.
Publications
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Sun S. W., Huang C. C., Wang Y. J., Liu Y. M., Chai W. G., F. Yang, Zhang J. W., Gao F., Chen R. S., Li Y., Bu D. B. “Towards automated identification of glycan branching patterns using multistage mass spectrometry with intelligent precursor selection." Glycobiology, (2016);1458.
