Global

Bioinformatics & Systems Biology Experts

Yong Tian


Institute of Biophysics
Chinese Academy of Sciences
China

Biography

1997-2002   Ph.D., Genetics Department of Medical Genetics Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China. 1992-1997   M.D., Medicine Department of Clinical Medicine, School of Medicine Beijing Medical University, Beijing, China RESEARCH EXPERIENCE 2009-Present  Professor, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China Research direction: Establishing animal research center in IBP, including transgene and gene targeting core facility in IBP. 2002-2008  Postdoctoral Research Associate, St. Jude Children’s Research Hospital, Memphis, TN, USA Research direction: Studying mouse models of human genetic diseases. 2000-2001  Ph.D., co-supervised by Department of Clinical Genetics, Erasmus University, Rotterdam, the Netherlands 1997-2002  Ph.D., supervised by Department of Medical Genetics, Peking Union Medical College& Chinese Academy of Medical Sciences, Beijing, China 1997-2002   Ph.D., Genetics Department of Medical Genetics Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China. 1992-1997   M.D., Medicine Department of Clinical Medicine, School of Medicine Beijing Medical University, Beijing, China RESEARCH EXPERIENCE 2009-Present  Professor, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China Research direction: Establishing animal research center in IBP, including transgene and gene targeting core facility in IBP. 2002-2008  Postdoctoral Research Associate, St. Jude Children’s Research Hospital, Memphis, TN, USA Research direction: Studying mouse models of human genetic diseases. 2000-2001  Ph.D., co-supervised by Department of Clinical Genetics, Erasmus University, Rotterdam, the Netherlands 1997-2002  Ph.D., supervised by Department of Medical Genetics, Peking Union Medical College& Chinese Academy of Medical Sciences, Beijing, China

Research Interest

1、Modeling human disease with human disease specific iPS and ES cell differentiation and its functional assay using genome editing technique (CRISPR/Cas9). 2、Generation and characterization of transgenic and knockout mouse model for human disease using CRISPR/Cas9 technique.

Publications

  • Liu B, Ye B, Zhu X, Huang G, Zhu P, Yang L, Du Y, Wu J, Meng S, Tian Y*, Fan Z*. IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development. Nat Commun. 2017 Aug 10. doi:10.1038/s41467-017-00235-x.

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