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Bioinformatics & Systems Biology Experts

Yu, Shan


Institute of Automation
Chinese Academy of Sciences
China

Biography

Dr. Yu, Shan is currently working as a Professor in the Department of Institute of Automation, Chinese Academy of Sciences , China. Dr. Yu, Shan is currently working as a Professor in the Department of Institute of Automation, Chinese Academy of Sciences , China.

Research Interest

The fundamental challenge for systems neuroscience is to explain functions of the brain by studying neuronal activities. While a huge amount of knowledge has been accumulated regarding the behavior of single neurons, it is still far from clear how the brain achieves its remarkable feat as an organ of information processing, as well as how its functions are interrupted in various pathological conditions. To fill such an explanatory gap, we need to understand how numerous neurons, often with different response properties, can form an orchestrated network to perform computation, and how such computation is regulated according to the behavioral context. To develop such an intermediate-level description of neuronal information processing is my long-term goal. To this end, my research combine highly parallel electrophyiological recordings from macaque brain and advanced computational/theoretical approaches (e.g., network theory, information theory, statistical mechanics, etc) to investigate the structure and operation of neuronal networks, with focuses on understanding both how the brain works in normal conditions and the network mechanisms underlying major mental disorders.

Publications

  • Yu S, Yang H, Shriki O, Plenz D. (2014) Critical exponents, universality class, and thermodynamic "temperature" for the brain. In Criticality in Neural Systems, edited by Plenz D and Nieber E. Wiley-VCH

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