Zhang Zhihua
Professor
Beijing Institute of Genomics
Chinese Academy of Sciences
China
Biography
Dr. ZHANG Zhihua is a principal investigator at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences (CAS). He is an editorial board member of journal Genomics, Proteomics ＆ Bioinformatics since 2012. In 2006, he received his Ph.D. degree from Institute of Biophysics, Chinese Academy of Sciences; 2006-2011, Postdoctoral programs at University of Michigan, The Cold Spring Harbor Laboratory and the University of Texas at Dallas, where he devoted most of his time to studies of computational system biology; In 2011, he joined BIG as a PI for evolutionary and computational systems biology and was selectively supported by the CAS “100-talent Program”. He has undertaken many projects from 863, 973, General Program of National Nature Science Foundation of China (NSFC) etc.
Research Interest
ZHANG’s lab combines the methods of computational systems biology with the cutting-edge experimental technologies to study the structure and function of 3D genome.There are four major research interests in our group. 1. 3D Genome. 2. Long noncoding RNAs 3. The micro-evolution of the gene regulatory network (GRN). 4. Artificial intelligence and biomedical big data.
Publications
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Zhang Zhihua#. 2016. A Key to Genome Maze in 3D. Genomics, proteomics & bioinformatics 14: 4-6.
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Xu Bingxiang, Ge Hao, Zhang Zhihua#. 2017. An efficient and assumption-free method to approximate protein level distribution in the two-states gene expression model. Journal of theoretical biology 433: 1-7.
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Zhang Hui, Li Feifei, Jia Yan, Xu Bingxiang, Zhang Yiqun, Li Xiaoli, Zhang Zhihua#. 2017. Characteristic arrangement of nucleosomes is predictive of chromatin interactions at kilobase resolution. Nucleic acids research doi:10.1093/nar/gkx885.
