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Bioinformatics & Systems Biology Experts

Zusen Fan


Institute of Biophysics
Chinese Academy of Sciences
China

Biography

Dr. Zusen Fan, Professor, Mentor for Ph.D candidates. Deputy Director of the CAS Key Laboratory for Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, CAS. Dr. Fan obtained Ph.D degree in the Medical School of Shanghai Jiaotong University in 1998, and then got postdoctoral training in Harvard Medical School, and promoted Instructor of Harvard University in 2003. Eventually he was recruited to the Institute of Biophysics of CAS as “Hundred Talents Project” professor in 2004. In 2005, he got the National Outstanding Youth Grant from NSFC. In 2006, he was granted as the National Talents of “Hundred-Thousand-Tenthousand Program”. In 2008, Dr. Fan was evaluated as “Excellent” at the final evaluation of the “Hundred Talents Project”. In 2010, he was awarded as the State Council Expert for Special Allowance. In 2014, he was granted with Tan Jiazhen Life Sciences Innovation Award. In 2014, he was selected as Outstanding Professor of the CAS University. In 2015, he was recruited to the CAS Center for Excellence in Biomacromolecules. In 2016, he was awarded to CAS Outstanding Graduate Tutor Award. Fan Lab focuses on these three major research fields: 1) Regulation of immune cell transdifferentiation and mechanisms of infection immunity; 2) Non-coding RNA and regulation of immunity; 3) Mechanisms of self-renewal of cancer stem cells and tumor immunotherapy. Dr. Zusen Fan, Professor, Mentor for Ph.D candidates. Deputy Director of the CAS Key Laboratory for Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, CAS. Dr. Fan obtained Ph.D degree in the Medical School of Shanghai Jiaotong University in 1998, and then got postdoctoral training in Harvard Medical School, and promoted Instructor of Harvard University in 2003. Eventually he was recruited to the Institute of Biophysics of CAS as “Hundred Talents Project” professor in 2004. In 2005, he got the National Outstanding Youth Grant from NSFC. In 2006, he was granted as the National Talents of “Hundred-Thousand-Tenthousand Program”. In 2008, Dr. Fan was evaluated as “Excellent” at the final evaluation of the “Hundred Talents Project”. In 2010, he was awarded as the State Council Expert for Special Allowance. In 2014, he was granted with Tan Jiazhen Life Sciences Innovation Award. In 2014, he was selected as Outstanding Professor of the CAS University. In 2015, he was recruited to the CAS Center for Excellence in Biomacromolecules. In 2016, he was awarded to CAS Outstanding Graduate Tutor Award. Fan Lab focuses on these three major research fields: 1) Regulation of immune cell transdifferentiation and mechanisms of infection immunity; 2) Non-coding RNA and regulation of immunity; 3) Mechanisms of self-renewal of cancer stem cells and tumor immunotherapy.

Research Interest

1) Discovery of new lncRNAs in innate immune cell subsets and definition of their regulatory roles in immune responses 2) Identification of new innate immune cell subsets, definition of their effector functions and their mechanisms of transdifferentiation 3) Elucidation of self-renewal of cancer stem cells and strategies for tumor immunology

Publications

  • Xia P, Ye B, Wang S, Zhu X, Du Y, Xiong Z, Tian Y*, Fan Z*. Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016;17(4):369-78.

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