Chan Tak Cheung, Anthony
Associate Dean
Oncology
Chinese University of Hong Kong
China
Biography
Professor Anthony Chan is Li Shu Fan Professor of Clinical Oncology, Chief of Service, Department of Clinical Oncology, Director of the Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute and Chief Director of Phase 1 Clinical Trial Centre at the Chinese University of Hong Kong. Professor Chan conducted pivotal studies setting the new treatment standard in multimodality approaches in nasopharynx cancer, developed the clinical application of the biomarker EBV DNA and pioneered immunotherapeutic and targeted therapeutics in this disease. He has published over 240 peer-reviewed papers, 40 book chapters and reviews, and delivered over 130 international lectures. He has served on the Editorial Board of Journal of Clinical Oncology and is currently Associate Editor of Annals of Oncology.
Research Interest
Nasopharyngeal Carcinoma, Colorectal Cancer, Hepatocellular Carcinoma
Publications
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Chan A.T.C., Tao Q., Robertson K.D., Flinn I.W., Mann R.B., Klenck B., Kwan W.H., Leung WT., Johnson P.J., Ambinder R.F. Azacytidine induces demethylation of the Epstein-Barr virus genome in tumors in patients. J Clin Oncol 04;22:1373-81.
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Chan A.T.C., Leung S.F., Ngan R.K.C., Teo P.M.L., Lau W.H., Kwan W.H., Hui E.P., Cheung F.Y., Yeo W., Yiu H.H., Yu K.H., Chiu K.W., Chan D.T., Mok T.S.K., Yuen K.T., Mo F.K.F., Lai M.M.P., Ma B.B.Y., Johnson P.J., Zee B.C.Y. Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma. J Natl Cancer Inst 05;97:536-9.
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Chan A.T.C., Hsu M.M., Goh B.C., Hui E.P., Liu T.W., Millward M.J., Chang A.Y.C., Hong R.L., Whang-Peng J., Ma B.B.Y., Mueser M., Amellal N., Lin X. A multi-center, phase II study of Cetuximab in combination with carboplatin in patients with recurrent or metastatic nasopharyngeal carcinoma. J Clin Oncol 05;23:3568-76.
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Leung S.F., Zee B., Ma B.Y., Hui E.P., Mo F., Lai M., Chan A.K.C., Chan L.Y.S., Kwan W.H., Lo Y.M.D., Chan A.T.C. Combined clinical- biomolecular staging for cancer: the model of nasopharyngeal cancer. J Clin Oncol 06;24:5414-8.
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Kam M.M.K., Leung S.F., Zee B., Chau R.M.C., Suen J.J.S., Mo F., Lai M., Ho R., Cheung K.Y., Yu B.K.H., Chiu S.K.W., Choi P.H.K., Teo P.M.L., Kwan W.H., Chan A.T.C. Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients. J Clin Oncol 07;25:4873-9.
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Wee J.T., Anderson B.O., Corry J., D’Cruz A., Soo K.C., Qian C.N., Chua D.T., Hicks R.J., Goh C.H., Khoo J.B., Ong S.C., Forastiere A.A., Chan A.T.C. Management of the neck after chemoradiotherapy for head and neck cancers in Asia: consensus statement from the Asian Oncology Summit 2009. Lancet Oncol 09;10:1086-92.
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Hui E.P., Ma B.B.Y., Leung S.F., King A.D., Mo F., Kam M.K.M., Yu B.K.H., Chiu S.K.W., Kwan W.H., Ho R., Chan I., Ahuja A.T., Zee B.C.Y., Chan A.T.C. Randomized phase II trial of concurrent cisplatin-radiotherapy with or without neoadjuvant chemotherapy using docetaxel and cisplatin in advanced nasopharyngeal carcinoma. J Clin Oncol 09;27:242-9.
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Hui E.P., Taylor G.S., Hui J., Ma B.B.Y., Chan S.L., Ho R., Wong W.L., Wilson St., Johnson B.F., Edwards C., Stocken D.D., Rickinson A.B., Steven N.M., Chan A.T.C. Phase 1 trial of recombinant Modified Vaccinia Ankara encoding EBV-encoded tumor antigens in nasopharyngeal carcinoma patients. Cancer Research 13;73:1676-88.
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Lee A.W.M, Ma B.B.Y., Ng W.T., Chan A.T.C. The management of nasopharyngeal carcinoma – current practice and future perspective. J Clin Oncol 10;33(29):3356-64. Epub 2015 Sep 8.
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Chua M.L.K., Wee J.T.S., Hui E.P., Chan A.T.C. Nasopharyngeal carcinoma. Lancet. 387(10022):1012-24. Epub 2015 Aug 28.
