Wu Huijian
Professor
School of Life Science & Medicine
Dalian University of Technology
China
Biography
Wu Huijian is a Professor and doctoral tutor of Life and Medicine College of Dalian University of Technology, China. His research projects are 1. CLOCK in breast cancer in the role of research (the Ministry of Education Ph.D. 2. The apparent genetic mechanism of tumor cells (cultivated by the Ministry of Education); 3. CLOCK regulation of ERα and its role in the development of breast cancer (National Natural Science Foundation of China: 31171353 ); 4. The apparent genetic mechanism of DNA methylation in tumor cells (Ministry of Science and Technology ""973"" project: 2011CB504201 ); 5. Modulation of SUMO -modified AhR and its role in the development and progression of breast cancer (National Natural Science Foundation of China: 31271500 ).
Research Interest
Bioengineering, Oncology
Publications
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Xing X, Bi H, Chang AK, Zang MX, Wang M, et al. (2012) SUMOylation of AhR modulates its activity and stability through inhibiting its ubiquitination. J Cell Physiol 227: 3812-3819.
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Li S, Wang M, Ao X, Chang AK, Yang C, et al. (2013) CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-α. Oncogene 10: 4883-4891.
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Yang C, Li S, Wang M, Chang AK, Liu Y, et al. (2013) PTEN suppresses the oncogenic function of AIB1 through decreasing its protein security via action involving Fbw7α. Molecular Cancer 21: 21.
