Liu Ju
Associate Professor
School of Pharmaceutical Science
Eastern Liaoning University
China
Biography
LIU Ju obtains his B.Sc in Anshan Normal University and master’s degree in Liaoning University in China, with emphasis on medicinal and organic chemistry. Currently he is the Associate researcher in School of Pharmaceutical Sciences at Liaoning University. The focus of his research is on the structure-based drug discovery and drug preparation technology. He has participated in several National Projects in the area of antitumor and bacterial resistance agents including potent c-Met, Flt-3, ALK, Raf inhibitor and Gambogic Acid derivatives, ect. To date, more than 10 scientific projects are undertaken in his group and 40 scientific papers are published in peer-reviewed journals. In addition, 7 patent applications are submitted by his group.
Research Interest
1. Structure-based drug design and discovery 2. Drug preparation technology
Publications
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Ju Liu, Duan-Zheng Song, Yan-Qiu Tian, et al. Synthesis, Crystal Structure, and Biological Activity of 5-(4-fluorophenyl)-N,N-dimethyl -7-(trifluoromethyl)pyrazolo [1,5-a]pyrimidine-3-carboxamide[J]. Journal of Chemical Research, 2016, 40: 107-109. (SCI)
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Ju Liu, Xin-Wei Zhang, Duan-Zheng Song, et al. Synthesis of several new 1-arylpyrazolo[3,4-d]pyrimidines containing amide moiety[J]. Journal of Chemical Research, 2016, 40: 92-94. (SCI)
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Ju Liu, Minhua Nie, Yanjing Wang, et al. Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors [J]. European Journal of Medicinal Chemistry, 2016, 123: 431-446. (SCI)